VLDLR Antikörper (C-Term)

Produktnummer ABIN3024046

Der Maus Monoklonal anti-VLDLR Antikörper (Klon VLPR-1) (ABIN3024046) detektiert spezifisch VLDLR in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für VLDLR Antikörper (C-Term) (ABIN3024046)

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser VLDLR Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: VLPR-1

Produktdetails anti-VLDLR Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: VLDLR Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A human recombinant partial protein from the C-terminal region was used as the immunogen for this VLDLR antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the VLDLR antibody to be titered up or down for optimal performance.

1. Staining of FFPE tissue is enhanced by boiling sections in 10 mM Tris with 1 mM EDTA, pH 9 for 10-20 min followed by cooling at RT for 20 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the VLDLR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu VLDLR

Target: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Andere Bezeichnung: VLDLR

Hintergrund: Very Low Density Lipoprotein Receptor (VLDLR/VLDL receptor) is a member of the LDL receptor gene family which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDL receptor is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development.

UniProt: P98155

Pathways: Cellular Response to Molecule of Bacterial Origin