UACA Antikörper

Produktnummer ABIN3024023

Dieser Maus Monoklonal Antikörper detektiert spezifisch UACA in WB, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für UACA Antikörper (ABIN3024023)

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: AE-5

Produktdetails anti-UACA Antikörper

Verwendungszweck: UACA Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the UACA antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the UACA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu UACA

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Andere Bezeichnung: UACA

Hintergrund: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity