UACA Antikörper

Produktnummer ABIN3024023

Dieses Maus Monoklonal-Antikörper erkennt spezifisch UACA in WB, IF und FACS. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für UACA Antikörper (ABIN3024023)

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser UACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: AE-5

Produktdetails anti-UACA Antikörper

Aufreinigung: Protein G affinity chromatography

Immunogen: Nuclei of myeloid leukemia biopsy cells were used as the immunogen for the UACA antibody.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the UACA antibody should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence: 0.5-1 μg/mL,Western blot: 0.5-1 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the UACA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Details zu UACA

Target: UACA (Uveal Autoantigen With Coiled Coil Domains And Ankyrin Repeats (UACA))

Andere Bezeichnung: UACA

Hintergrund: UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.

Pathways: Positive Regulation of Endopeptidase Activity