Fascin Antikörper (AA 394-493)

Produktnummer ABIN3023682

Dieses Anti-Fascin-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Fascin in WB, IHC und IF. Geeignet für Human.

Kurzübersicht für Fascin Antikörper (AA 394-493) (ABIN3023682)

Target: Fascin (FSCN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fascin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Fascin Antikörper

Bindungsspezifität: AA 394-493

Sequenz: FIGCRKVTGT LDANRSSYDV FQLEFNDGAY NIKDSTGKYW TVGSDSAVTS SGDTPVDFFF EFCDYNKVAI KVGGRYLKGD HAGVLKASAE TVDPASLWEY

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 394-493 of human Fascin/Fascin/FSCN1 (NP_003079.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Fascin

Target: Fascin (FSCN1)

Andere Bezeichnung: FSCN1

Hintergrund: This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15.,FSCN1,FAN1,HSN,SNL,p55,fascin,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Actins,FSCN1

Molekulargewicht: 54 kDa

Gen-ID: 6624

UniProt: Q16658