HMGB1 Antikörper (AA 100-200)
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- Target Alle HMGB1 Antikörper anzeigen
- HMGB1 (High Mobility Group Box 1 (HMGB1))
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Bindungsspezifität
- AA 100-200
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser HMGB1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- SAFFLFCSEY RPKIKGEHPG LSIGDVAKKL GEMWNNTAAD DKQPYEKKAA KLKEKYEKDI AAYRAKGKPD AAKKGVVKAE KSKKKKEEEE DEEDEEDEEE E
- Kreuzreaktivität
- Human, Maus, Ratte
- Produktmerkmale
- Polyclonal Antibodies
- Aufreinigung
- Affinity purification
- Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 100-200 of human HMGB1 (NP_002119.1).
- Isotyp
- IgG
- Top Product
- Discover our top product HMGB1 Primärantikörper
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- Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness." in: Toxicology and applied pharmacology, Vol. 350, pp. 64-77, (2018) (PubMed).
: "Blockade of β-catenin signaling attenuates toluene diisocyanate-induced experimental asthma." in: Allergy, Vol. 72, Issue 4, pp. 579-589, (2017) (PubMed).
: "Enriched housing promotes post-stroke functional recovery through astrocytic HMGB1-IL-6-mediated angiogenesis." in: Cell death discovery, Vol. 3, pp. 17054, (2017) (PubMed).
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Increased butyrate priming in the gut stalls microbiome associated-gastrointestinal inflammation and hepatic metabolic reprogramming in a mouse model of Gulf War Illness." in: Toxicology and applied pharmacology, Vol. 350, pp. 64-77, (2018) (PubMed).
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- Target
- HMGB1 (High Mobility Group Box 1 (HMGB1))
- Andere Bezeichnung
- HMGB1 (HMGB1 Produkte)
- Hintergrund
- This gene encodes a protein that belongs to the High Mobility Group-box superfamily. The encoded non-histone, nuclear DNA-binding protein regulates transcription, and is involved in organization of DNA. This protein plays a role in several cellular processes, including inflammation, cell differentiation and tumor cell migration. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants that encode the same protein.,HMG-1,HMG1,HMG3,SBP-1,HMGB1,Epigenetics & Nuclear Signaling,Histones,RNA Binding,Cell Biology & Developmental Biology,Apoptosis,HMGB1
- Molekulargewicht
- 24 kDa
- Gen-ID
- 3146
- UniProt
- P09429
- Pathways
- p53 Signalweg, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, Inflammasome
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