UHRF1 Antikörper (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1)

Details for Product anti-UHRF1 Antibody No. ABIN3023232
Target
Reaktivität
Human
55
9
3
3
2
2
2
1
Wirt
Kaninchen
34
18
7
1
Klonalität
Polyklonal
Konjugat
Dieser UHRF1 Antikörper ist unkonjugiert
3
3
3
3
3
3
Applikation
Chromatin Immunoprecipitation (ChIP), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
60
41
12
9
8
8
5
3
3
1
1
Optionen
Immunogen Recombinant protein of human UHRF1
Isotyp IgG
Reinigung Affinity purification
Target
Andere Bezeichnung UHRF1 (UHRF1 Antibody Abstract)
Hintergrund UHRF1, also named as ICBP90, NP95 and RNF106, is a putative E3 ubiquitin-protein ligase. It may participate in methylation-dependent transcriptional regulation. UHRF1 binds to inverted 5-CCAAT-3 box 2 in the TOP2A promoter, and activates TOP2A expression. It is important for G1/S transition and may be involved in DNA repair and chromosomal stability. UHRF1s ability to repress its direct target gene expression is dependent on PHD(UHRF1) binding to unmodified H3R2.
Synonyms: FLJ21925, ICBP90, MGC138707, Np95, RNF106, hNP95
Gen-ID 29128
UniProt Q96T88
Applikations-hinweise Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:20-1:50, IP: 1:20-1:50, CHIP: 1:20-1:50
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze / thaw cycles
Lagerung -20 °C/-80 °C
Bilder
Image no. 1 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunofluorescence analysis of U2OS cells using UHRF1 antibody.
Image no. 2 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Western blot analysis of extracts of various cell lines, using UHRF1 antibody.
Image no. 3 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunohistochemistry of paraffin-embedded human tonsil using UHRF1 antibody.
Image no. 4 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunohistochemistry of paraffin-embedded human lung cancer using UHRF1 antibody.
Image no. 5 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunohistochemistry of paraffin-embedded human colon using UHRF1 antibody.
Image no. 6 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunohistochemistry of paraffin-embedded human colon carcinoma using UHRF1 antibody.
Image no. 7 for anti-Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1) antibody (ABIN3023232) Immunohistochemistry of paraffin-embedded human gastric cancer using UHRF1 antibody.