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UHRF1 Antikörper (AA 616-755)

UHRF1 Reaktivität: Human WB, ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2A8C7 unconjugated
Produktnummer ABIN5542544
  • Target Alle UHRF1 Antikörper anzeigen
    UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
    Bindungsspezifität
    • 10
    • 9
    • 8
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 616-755
    Reaktivität
    • 46
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 27
    • 21
    • 1
    • 1
    Maus
    Klonalität
    • 28
    • 22
    Monoklonal
    Konjugat
    • 36
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser UHRF1 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 22
    • 12
    • 8
    • 7
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human UHRF1 (AA: 616-755) expressed in E. coli.
    Klon
    2A8C7
    Isotyp
    IgG1
    Top Product
    Discover our top product UHRF1 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: , FCM:
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    UHRF1 (Ubiquitin-Like, Containing PHD and RING Finger Domains, 1 (UHRF1))
    Andere Bezeichnung
    UHRF1 (UHRF1 Produkte)
    Synonyme
    ICBP90 antikoerper, Np95 antikoerper, RNF106 antikoerper, hNP95 antikoerper, hUHRF1 antikoerper, AL022808 antikoerper, NP95 antikoerper, fb97f09 antikoerper, wu:fb97f09 antikoerper, zgc:63539 antikoerper, UHRF1 antikoerper, ubiquitin like with PHD and ring finger domains 1 antikoerper, ubiquitin-like, containing PHD and RING finger domains, 1 antikoerper, ubiquitin-like with PHD and ring finger domains 1 antikoerper, UHRF1 antikoerper, Uhrf1 antikoerper, uhrf1 antikoerper
    Hintergrund

    Description: This gene encodes a member of a subfamily of RING-finger type E3 ubiquitin ligases. The protein binds to specific DNA sequences, and recruits a histone deacetylase to regulate gene expression. Its expression peaks at late G1 phase and continues during G2 and M phases of the cell cycle. It plays a major role in the G1/S transition by regulating topoisomerase IIalpha and retinoblastoma gene expression, and functions in the p53-dependent DNA damage checkpoint. It is regarded as a hub protein for the integration of epigenetic information. This gene is up-regulated in various cancers, and it is therefore considered to be a therapeutic target. Multiple transcript variants encoding different isoforms have been found for this gene. A related pseudogene exists on chromosome 12.,

    Aliases: Np95, hNP95, ICBP90, RNF106, TDRD22, hUHRF1, huNp95

    Molekulargewicht
    89.8 kDa
    Gen-ID
    29128
    HGNC
    5335
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