Thrombospondin 1 Antikörper (AA 80-360)
Kurzübersicht für Thrombospondin 1 Antikörper (AA 80-360) (ABIN3022979)
Target
Alle Thrombospondin 1 (THBS1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 80-360
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Sequenz
- DAVRAEKGFL LLASLRQMKK TRGTLLALER KDHSGQVFSV VSNGKAGTLD LSLTVQGKQH VVSVEEALLA TGQWKSITLF VQEDRAQLYI DCEKMENAEL DVPIQSVFTR DLASIARLRI AKGGVNDNFQ GVLQNVRFVF GTTPEDILRN KGCSSSTSVL LTLDNNVVNG SSPAIRTNYI GHKTKDLQAI CGISCDELSS MVLELRGLRT IVTTLQDSIR KVTEENKELA NELRRPPLCY HNGVQYRNNE EWTVDSCTEC HCQNSVTICK KVSCPIMPCS N
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-360 of human THBS1 (NP_003237.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).
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: "Hippo component YAP promotes focal adhesion and tumour aggressiveness via transcriptionally activating THBS1/FAK signalling in breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 175, (2018) (PubMed).
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- Thrombospondin 1 (THBS1)
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Andere Bezeichnung
- THBS1
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Hintergrund
- The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis.,THBS1,THBS,THBS-1,TSP,TSP-1,TSP1,Cancer,Invasion and Metastasis,Cell Biology & Developmental Biology,Cell Adhesion,Endocrine & Metabolism,Neuroscience,Cell Type Marker,Stem Cells,Cardiovascular,Angiogenesis,Angiogenic inhibitory factors,Blood,Hypoxia,Astrocyte marker,THBS1
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Molekulargewicht
- 120 kDa/129 kDa
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Gen-ID
- 7057
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UniProt
- P07996
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Pathways
- Autophagie
Target
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