BUB1
Reaktivität: Human
ELISA, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB,1:500 - 1:2000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid freeze / thaw cycles
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
BUB1
(Budding Uninhibited By Benzimidazoles 1 Homolog (Yeast) (BUB1))
Andere Bezeichnung
BUB1
Hintergrund
This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants.,BUB1,BUB1A,BUB1L,hBUB1,Cancer,Signal Transduction,Kinase,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Cell Cycle,Centromere,BUB1