BMPR1A Antikörper (AA 24-200)

Produktnummer ABIN3022600

Dieses Anti-BMPR1A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BMPR1A in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für BMPR1A Antikörper (AA 24-200) (ABIN3022600)

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BMPR1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BMPR1A Antikörper

Bindungsspezifität: AA 24-200

Sequenz: QNLDSMLHGT GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF AIIEEDDQGE TTLASGCMKY EGSDFQCKDS PKAQLRRTIE CCRTNLCNQY LQPTLPPVVI GPFFDGSIRW LVLLISMAVC IIAMIIFSSC FCYKHYCKSI SSRRRYNRDL EQDEAFI

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 24-200 of human BMPR1A (NP_004320.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-BMPR1A Antikörper (ABIN3022600)

Chang, Lin, Fu, Wang, Han, Fan: "MicroRNA-195-5p Regulates Osteogenic Differentiation of Periodontal Ligament Cells Under Mechanical Loading." in: Journal of cellular physiology, Vol. 232, Issue 12, pp. 3762-3774, (2017) (PubMed).

Details zu BMPR1A

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Andere Bezeichnung: BMPR1A

Hintergrund: The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.,BMPR1A,10q23del,ACVRLK3,ALK3,CD292,SKR5,Signal Transduction,Kinase,Cell Biology & Developmental Biology,Growth factor,Endocrine & Metabolism,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,Mesenchymal Stem Cells,Cardiovascular,Heart,Cardiogenesis,Receptors,BMPR1A

Molekulargewicht: 60 kDa

Gen-ID: 657

UniProt: P36894

Pathways: Stem Cell Maintenance