Kallikrein 1 Antikörper (AA 25-262)
Kurzübersicht für Kallikrein 1 Antikörper (AA 25-262) (ABIN3022582)
Target
Alle Kallikrein 1 (KLK1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-262
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Sequenz
- IVGGWECEQH SQPWQAALYH FSTFQCGGIL VHRQWVLTAA HCISDNYQLW LGRHNLFDDE NTAQFVHVSE SFPHPGFNMS LLENHTRQAD EDYSHDLMLL RLTEPADTIT DAVKVVELPT EEPEVGSTCL ASGWGSIEPE NFSFPDDLQC VDLKILPNDE CKKAHVQKVT DFMLCVGHLE GGKDTCVGDS GGPLMCDGVL QGVTSWGYVP CGTPNKPSVA VRVLSYVKWI EDTIAENS
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 25-262 of human KLK1 (NP_002248.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Kallikrein 1 (KLK1)
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Andere Bezeichnung
- KLK1
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Hintergrund
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. This protein is functionally conserved in its capacity to release the vasoactive peptide, Lys-bradykinin, from low molecular weight kininogen.,KLK1,KLKR,Klk6,hK1,Cancer,Invasion and Metastasis,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,Cardiovascular,Angiogenesis,Blood,Coagulation,Serum Proteins,KLK1
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Molekulargewicht
- 23 kDa/28 kDa
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Gen-ID
- 3816
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UniProt
- P06870
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Pathways
- Komplementsystem
Target
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