RASSF1 Antikörper (AA 101-340)

Produktnummer ABIN3021712

Dieses Anti-RASSF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RASSF1 in WB. Geeignet für Human.

Kurzübersicht für RASSF1 Antikörper (AA 101-340) (ABIN3021712)

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RASSF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RASSF1 Antikörper

Bindungsspezifität: AA 101-340

Sequenz: CCGPRDLGWE PAVERDTNVD EPVEWETPDL SQAEIEQKIK EYNAQINSNL FMSLNKDGSY TGFIKVQLKL VRPVSVPSSK KPPSLQDARR GPGRGTSVRR RTSFYLPKDA VKHLHVLSRT RAREVIEALL RKFLVVDDPR KFALFERAER HGQVYLRKLL DDEQPLRLRL LAGPSDKALS FVLKENDSGE VNWDAFSMPE LHNFLRILQR EEEEHLRQIL QKYSYCRQKI QEALHACPLG

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_009113.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu RASSF1

Target: RASSF1 (Ras Association (RalGDS/AF-6) Domain Family Member 1 (RASSF1))

Andere Bezeichnung: RASSF1

Hintergrund: This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.,RASSF1,123F2,NORE2A,RASSF1A,RDA32,REH3P21,Epigenetics & Nuclear Signaling,DNA Damage & Repair,Cancer,Tumor suppressors,Signal Transduction,G protein signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cell Cycle,Cell cycle inhibitors,RASSF1

Molekulargewicht: 8 kDa/9 kDa/16 kDa/21 kDa/31 kDa/38 kDa/39 kDa

Gen-ID: 11186

UniProt: Q9NS23