FGF10 Antikörper (AA 40-208)

Produktnummer ABIN3021706

Der Kaninchen Polyklonal Anti-FGF10-Antikörper wurde für WB validiert. Er ist geeignet, FGF10 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für FGF10 Antikörper (AA 40-208) (ABIN3021706)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FGF10 Antikörper

Bindungsspezifität: AA 40-208

Sequenz: LGQDMVSPEA TNSSSSSFSS PSSAGRHVRS YNHLQGDVRW RKLFSFTKYF LKIEKNGKVS GTKKENCPYS ILEITSVEIG VVAVKAINSN YYLAMNKKGK LYGSKEFNND CKLKERIEEN GYNTYASFNW QHNGRQMYVA LNGKGAPRRG QKTRRKNTSA HFLPMVVHS

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-208 of human FGF10 (NP_004456.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-FGF10 Antikörper (ABIN3021706)

Sun, Cui, Gao, Pan, Zhou, Huang, Lan, Wei, Liu, Liu, Xian: "TGF-α Overexpression in Breast Cancer Bone Metastasis and Primary Lesions and TGF-α Enhancement of Expression of Procancer Metastasis Cytokines in Bone Marrow Mesenchymal Stem Cells." in: BioMed research international, Vol. 2018, pp. 6565393, (2018) (PubMed).

Details zu FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF10

Hintergrund: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.,FGF10,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Embryonic Stem Cells,Cardiovascular,Angiogenesis,FGF10

Molekulargewicht: 23 kDa

Gen-ID: 2255

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus