CD86 Antikörper (AA 30-247)

Produktnummer ABIN3021701

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CD86 in WB und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für CD86 Antikörper (AA 30-247) (ABIN3021701)

Target: CD86

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD86 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-CD86 Antikörper

Bindungsspezifität: AA 30-247

Sequenz: AYFNETADLP CQFANSQNQS LSELVVFWQD QENLVLNEVY LGKEKFDSVH SKYMGRTSFD SDSWTLRLHN LQIKDKGLYQ CIIHHKKPTG MIRIHQMNSE LSVLANFSQP EIVPISNITE NVYINLTCSS IHGYPEPKKM SVLLRTKNST IEYDGIMQKS QDNVTELYDV SISLSVSFPD VTSNMTIFCI LETDKTRLLS SPFSIELEDP QPPPDHIP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-247 of human CD86 (NP_787058.4).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-CD86 Antikörper (ABIN3021701)

Shi, Chen, Li, Sun, Cui, Ma: "The observed difference of RAW264.7 macrophage phenotype on mineralized collagen and hydroxyapatite." in: Biomedical materials (Bristol, England), Vol. 13, Issue 4, pp. 041001, (2018) (PubMed).

Rokade, Kishore, Madan: "Surfactant protein D regulates murine testicular immune milieu and sperm functions." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 77, Issue 3, (2017) (PubMed).

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86

Hintergrund: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.,B7-2,B7.2,B70,CD28LG2,LAB72,CD86,Immunology & Inflammation,CD markers,Stem Cells,Hematopoietic Progenitors,CD86

Molekulargewicht: 12 kDa/24 kDa/28 kDa/31 kDa/37 kDa

Gen-ID: 942

UniProt: P42081

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation