MMP7 Antikörper (AA 18-267)

Produktnummer ABIN3021103

Der Kaninchen Polyklonal Anti-MMP7-Antikörper wurde für WB, IHC und IF validiert. Er ist geeignet, MMP7 in Proben von Human zu detektieren.

Kurzübersicht für MMP7 Antikörper (AA 18-267) (ABIN3021103)

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-MMP7 Antikörper

Bindungsspezifität: AA 18-267

Sequenz: LPLPQEAGGM SELQWEQAQD YLKRFYLYDS ETKNANSLEA KLKEMQKFFG LPITGMLNSR VIEIMQKPRC GVPDVAEYSL FPNSPKWTSK VVTYRIVSYT RDLPHITVDR LVSKALNMWG KEIPLHFRKV VWGTADIMIG FARGAHGDSY PFDGPGNTLA HAFAPGTGLG GDAHFDEDER WTDGSSLGIN FLYAATHELG HSLGMGHSSD PNAVMYPTYG NGDPQNFKLS QDDIKGIQKL YGKRSNSRKK

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 18-267 of human MMP7 (NP_002414.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MMP7

Target: MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))

Andere Bezeichnung: MMP7

Hintergrund: This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers.,MMP7,MMP-7,MPSL1,PUMP-1,Cancer,Tumor biomarkers,Invasion and Metastasis,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,MMPs,Ubiquitin,Cardiovascular,Angiogenesis,MMP7

Molekulargewicht: 29 kDa

Gen-ID: 4316

UniProt: P09237

Pathways: Production of Molecular Mediator of Immune Response