GRB2 Antikörper (AA 198-217)
Kurzübersicht für GRB2 Antikörper (AA 198-217) (ABIN302091)
Target
Alle GRB2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 198-217
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Verwendungszweck
- Anti-GRB2 Purified
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Spezifität
- The polyclonal antibody recognizes Grb2, a highly conserved approximately 26 kDa intracellular adaptor protein. The immunogen has 100 % identity between man, cow, rat and mouse.
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Kreuzreaktivität (Details)
- Human, Other species Not tested
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Aufreinigung
- Purified by ligand affinity chromatography.
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Reinheit
- > 95 % (by SDS-PAGE)
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Immunogen
- Synthetic peptide corresponding to C-terminus of human Grb2 (amino acids 198-217).
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anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibody
GRB2 Reaktivität: Human, Maus, Ratte, Hund, Huhn ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibodyGRB2 Reaktivität: Human WB, IHC, IP, IF Wirt: Kaninchen Monoclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (C-Term) antibodyVerified GRB2 Reaktivität: Human, Maus, Ratte, Schwein WB, ELISA, IHC Wirt: Ziege Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (C-Term) antibodyKO Validated GRB2 Reaktivität: Human WB, IF, ICC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) antibodyKD Validated GRB2 Reaktivität: Human WB, ICC, FACS Wirt: Kaninchen Monoclonal 23GB6275 unconjugated Recombinant Antibody
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 1-217) antibodyGRB2 Reaktivität: Human, Maus, Ratte, Hund, Huhn, Frosch WB, IHC, IP, BI Wirt: Maus Monoclonal 81-GRB2 unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 89-118) antibodyGRB2 Reaktivität: Human WB, ELISA, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 89-118) antibodyGRB2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB15648 unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 187-216) antibodyGRB2 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB11305-11306 unconjugated
anti-Growth Factor Receptor-Bound Protein 2 (GRB2) (AA 156-217) antibodyGRB2 Reaktivität: Human WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Western blotting: Recommended dilution: 1-2 μg/mL, reducing conditions.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1 mg/mL
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Do not freeze.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2-8°C. Do not freeze.
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- GRB2 (Growth Factor Receptor-Bound Protein 2 (GRB2))
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Andere Bezeichnung
- GRB2
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Hintergrund
- Growth factor receptor bound protein 2,Grb2 (growth factor receptor-bound protein 2) is a highly conserved adaptor protein composed of central SH2 domain flanked by two terminal SH3 domains. Grb2 mediates coupling of receptor protein tyrosine kinases to a guanine nucleotide exchange factor Sos, thereby enabling the tyrosine kinases to stimulate activity of Ras and hence of MAP kinase pathway. Grb2 also can bind to receptor protein tyrosine phosphatases and affect their signaling.,ASH, NCKAP2
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Gen-ID
- 2885
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UniProt
- P62993
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Pathways
- RTK Signalweg, T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Actin Filament Polymerization, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, EGFR Downregulation
Target
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