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CARD8 Antikörper (AA 1-200)

Dieses Anti-CARD8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CARD8 in WB. Geeignet für Human.
Produktnummer ABIN3020898

Kurzübersicht für CARD8 Antikörper (AA 1-200) (ABIN3020898)

Target

Alle CARD8 Antikörper anzeigen
CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

Reaktivität

  • 39
  • 11
  • 10
Human

Wirt

  • 34
  • 5
Kaninchen

Klonalität

  • 36
  • 3
Polyklonal

Konjugat

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CARD8 Antikörper ist unkonjugiert

Applikation

  • 31
  • 13
  • 13
  • 6
  • 6
  • 4
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 1-200

    Sequenz

    MEARDKQVLR SLRLELGAEV LVEGLVLQYL YQEGILTENH IQEINAQTTG LRKTMLLLDI LPSRGPKAFD TFLDSLQEFP WVREKLKKAR EEAMTDLPAG DRLTGIPSHI LNSSPSDRQI NQLAQRLGPE WEPMVLSLGL SQTDIYRCKA NHPHNVQSQV VEAFIRWRQR FGKQATFQSL HNGLRAVEVD PSLLLHMLE

    Kreuzreaktivität

    Human

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CARD8 (NP_003796.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid freeze / thaw cycles

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))

    Andere Bezeichnung

    CARD8

    Hintergrund

    The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.,CARD8,CARDINAL,DACAR,DAKAR,NDPP,NDPP1,TUCAN,Cell Biology & Developmental Biology,Apoptosis,Caspases,CARD8

    Molekulargewicht

    32 kDa/44 kDa/48 kDa/55 kDa/60 kDa

    Gen-ID

    22900

    UniProt

    Q9Y2G2

    Pathways

    Positive Regulation of Endopeptidase Activity
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