Caspase 10 Antikörper (AA 220-521)

Produktnummer ABIN3020701

Der Kaninchen Polyklonal anti-Caspase 10 Antikörper wird verwendet zum Nachweis von Caspase 10 in Proben von Human. Er wurde validiert für WB.

Kurzübersicht für Caspase 10 Antikörper (AA 220-521) (ABIN3020701)

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Caspase 10 Antikörper

Bindungsspezifität: AA 220-521

Sequenz: VKTFLEALPQ ESWQNKHAGS NGNRATNGAP SLVSRGMQGA SANTLNSETS TKRAAVYRMN RNHRGLCVIV NNHSFTSLKD RQGTHKDAEI LSHVFQWLGF TVHIHNNVTK VEMEMVLQKQ KCNPAHADGD CFVFCILTHG RFGAVYSSDE ALIPIREIMS HFTALQCPRL AEKPKLFFIQ ACQGEEIQPS VSIEADALNP EQAPTSLQDS IPAEADFLLG LATVPGYVSF RHVEEGSWYI QSLCNHLKKL VPRHEDILSI LTAVNDDVSR RVDKQGTKKQ MPQPAFTLRK KLVFPVPLDA LS

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 220-521 of human Caspase-10 (NP_116759.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Caspase 10

Target: Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

Andere Bezeichnung: CASP10

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,CASP10,ALPS2,FLICE2,MCH4,caspase-10,Cancer,Invasion and Metastasis,Signal Transduction,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Caspases,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Ubiquitin,Death Receptor Signaling Pathway,Endocrine & Metabolism,Immunology & Inflammation,CASP10

Molekulargewicht: 28 kDa/31 kDa/51 kDa/54 kDa/58 kDa

Gen-ID: 843

UniProt: Q92851

Pathways: Apoptose, Caspase Kaskade in der Apoptose