alpha Fetoprotein Antikörper (AA 360-609)

Produktnummer ABIN3020666

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch alpha Fetoprotein in WB. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für alpha Fetoprotein Antikörper (AA 360-609) (ABIN3020666)

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser alpha Fetoprotein Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-alpha Fetoprotein Antikörper

Bindungsspezifität: AA 360-609

Sequenz: RRHPQLAVSV ILRVAKGYQE LLEKCFQTEN PLECQDKGEE ELQKYIQESQ ALAKRSCGLF QKLGEYYLQN AFLVAYTKKA PQLTSSELMA ITRKMAATAA TCCQLSEDKL LACGEGAADI IIGHLCIRHE MTPVNPGVGQ CCTSSYANRR PCFSSLVVDE TYVPPAFSDD KFIFHKDLCQ AQGVALQTMK QEFLINLVKQ KPQITEEQLE AVIADFSGLL EKCCQGQEQE VCFAEEGQKL ISKTRAALGV

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 360-609 of human Alpha-Fetoprotein (Alpha-Fetoprotein (AFP)) (NP_001125.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid freeze / thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-alpha Fetoprotein Antikörper (ABIN3020666)

Shen, Li, Zhang, Guo, Zhang, Zheng, Teng, Zhou, Guo, Huo: "A Comparative Proteome Profile of Female Mouse Gonads Suggests a Tight Link between the Electron Transport Chain and Meiosis Initiation." in: Molecular & cellular proteomics : MCP, Vol. 17, Issue 1, pp. 31-42, (2019) (PubMed).

Ma, Zhu, Tan, Mao, Tang, Shen, Zhang, Kuang, Fei, Yang, Wang: "Gpr110 deficiency decelerates carcinogen-induced hepatocarcinogenesis via activation of the IL-6/STAT3 pathway." in: American journal of cancer research, Vol. 7, Issue 3, pp. 433-447, (2017) (PubMed).

Details zu alpha Fetoprotein

Target: alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))

Andere Bezeichnung: AFP

Hintergrund: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.,AFPD,FETA,HPAFP,AFP,Cancer,Tumor biomarkers,Cell Biology & Developmental Biology,Stem Cells,Cardiovascular,Blood,Serum Proteins,AFP

Molekulargewicht: 68 kDa

Gen-ID: 174

UniProt: P02771

Pathways: C21-Steroid Hormone Metabolic Process