MYSM1 Antikörper (C-Term)

Produktnummer ABIN3017376

Produktdetails anti-MYSM1 Antikörper

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYSM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PLPYSQITCL VISEEISPDG SYRLPYKFEV QQMLEEPQWG LVFEKTRWII EKYRLSHSSV PMDKIFRRDS DLTCLQKLLE CMRKTLSKVT NCFMAEEFLT EIENLFLSNY KSNQENGVTE ENCTKELLM

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 700 to the C-terminus of human MYSM1 (NP_001078956.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu MYSM1

Target: MYSM1 (Myb-Like, SWIRM and MPN Domains 1 (MYSM1))

Andere Bezeichnung: MYSM1 (MYSM1 Produkte)

Hintergrund: Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.,MYSM1,2A-DUB,2ADUB,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Ubiquitin,MYSM1

Molekulargewicht: 26 kDa/66 kDa/95 kDa

Gen-ID: 114803

UniProt: Q5VVJ2

Pathways: Chromatin Binding