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CNTF Receptor alpha Antikörper (AA 190-340)

Dieses Anti-CNTF Receptor alpha-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CNTF Receptor alpha in WB. Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN3016492

Kurzübersicht für CNTF Receptor alpha Antikörper (AA 190-340) (ABIN3016492)

Target

Alle CNTF Receptor alpha (CNTFR) Antikörper anzeigen
CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Reaktivität

  • 35
  • 31
  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 47
  • 2
  • 1
Kaninchen

Klonalität

  • 49
  • 1
Polyklonal

Konjugat

  • 19
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CNTF Receptor alpha Antikörper ist unkonjugiert

Applikation

  • 33
  • 14
  • 14
  • 14
  • 9
  • 5
  • 5
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 15
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 190-340

    Sequenz

    NATAITFDEF TIVKPDPPEN VVARPVPSNP RRLEVTWQTP STWPDPESFP LKFFLRYRPL ILDQWQHVEL SDGTAHTITD AYAGKEYIIQ VAAKDNEIGT WSDWSVAAHA TPWTEEPRHL TTEAQAAETT TSTTSSLAPP PTTKICDPGE L

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 190-340 of human CNTFR (NP_001833.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:400 - 1:2000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Yong, Groeger, von Bremen, Ruf: "Ciliary Neurotrophic Factor (CNTF) and Its Receptors Signal Regulate Cementoblasts Apoptosis through a Mechanism of ERK1/2 and Caspases Signaling." in: International journal of molecular sciences, Vol. 23, Issue 15, (2022) (PubMed).

  • Target

    CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

    Andere Bezeichnung

    CNTFR

    Hintergrund

    This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.,CNTFR,Signal Transduction,Neuroscience,CNTFR

    Molekulargewicht

    40 kDa

    Gen-ID

    1271

    UniProt

    P26992

    Pathways

    JAK-STAT Signalweg, Feeding Behaviour
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