Vimentin Antikörper (AA 1-200)

Produktnummer ABIN3016292

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Vimentin in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human und wurde in 3+ Publikationen erwähnt.

Kurzübersicht für Vimentin Antikörper (AA 1-200) (ABIN3016292)

Target: Vimentin (VIM)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Vimentin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-Vimentin Antikörper

Bindungsspezifität: AA 1-200

Sequenz: MSTRSVSSSS YRRMFGGPGT ASRPSSSRSY VTTSTRTYSL GSALRPSTSR SLYASSPGGV YATRSSAVRL RSSVPGVRLL QDSVDFSLAD AINTEFKNTR TNEKVELQEL NDRFANYIDK VRFLEQQNKI LLAELEQLKG QGKSRLGDLY EEEMRELRRQ VDQLTNDKAR VEVERDNLAE DIMRLREKLQ EEMLQREEAE

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human Vimentin (NP_003371.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-Vimentin Antikörper (ABIN3016292)

Shen, Sun, Sun, Li, Wu, Li, Chen, Liu, Cui, Zhou: "ARRDC3 suppresses colorectal cancer progression through destabilizing the oncoprotein YAP." in: FEBS letters, Vol. 592, Issue 4, pp. 599-609, (2019) (PubMed).

Nie, Huang, Deng, Bao, Liu, Feng, Wang, Chen, Qi, Pan: "The purine receptor P2X7R regulates the release of pro-inflammatory cytokines in human craniopharyngioma." in: Endocrine-related cancer, Vol. 24, Issue 6, pp. 287-296, (2018) (PubMed).

Liu, Wang, Li, Zhang, Peng, Peng, Song, Qi, Pan: "TREM-1 expression in craniopharyngioma and Rathke's cleft cyst: its possible implication for controversial pathology." in: Oncotarget, Vol. 7, Issue 31, pp. 50564-50574, (2018) (PubMed).

Details zu Vimentin

Target: Vimentin (VIM)

Andere Bezeichnung: VIM

Hintergrund: This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.,CTRCT30,HEL113,Vimentin,VIM,vimentin,Cancer,Tumor biomarkers,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Stem Cells,Neural Stem Cells,Neural Stem Cell marker,VIM

Molekulargewicht: 53 kDa

Gen-ID: 7431

UniProt: P08670

Pathways: Caspase Kaskade in der Apoptose