Lamin B1 Antikörper (AA 397-586)
Kurzübersicht für Lamin B1 Antikörper (AA 397-586) (ABIN3015698)
Target
Alle Lamin B1 (LMNB1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 397-586
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Sequenz
- RVTVSRASSS RSVRTTRGKR KRVDVEESEA SSSVSISHSA SATGNVCIEE IDVDGKFIRL KNTSEQDQPM GGWEMIRKIG DTSVSYKYTS RYVLKAGQTV TIWAANAGVT ASPPTDLIWK NQNSWGTGED VKVILKNSQG EEVAQRSTVF KTTIPEEEEE EEEAAGVVVE EELFHQQGTP RASNRSCAIM
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 397-586 of human Lamin B1 (NP_005564.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200,IP,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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: "Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2." in: Molecular therapy. Nucleic acids, Vol. 9, pp. 195-206, (2017) (PubMed).
: "The C-ETS2-TFEB Axis Promotes Neuron Survival under Oxidative Stress by Regulating Lysosome Activity." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 4693703, (2017) (PubMed).
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: "Alleviation of Toxicity Caused by Overactivation of Pparα through Pparα-Inducible miR-181a2." in: Molecular therapy. Nucleic acids, Vol. 9, pp. 195-206, (2017) (PubMed).
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- Lamin B1 (LMNB1)
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Andere Bezeichnung
- LMNB1
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Hintergrund
- This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.,ADLD,LMN,LMN2,LMNB,Lamin B1,LMNB1,lamin-B1,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Cytoskeleton,Intermediate Filaments,LMNB1
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Molekulargewicht
- 66 kDa
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Gen-ID
- 4001
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UniProt
- P20700
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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