Abeta 1-42 Antikörper

Produktnummer ABIN2961828

Dieses Maus Monoklonal-Antikörper erkennt spezifisch Abeta 1-42 in WB, IHC, IP, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Abeta 1-42 Antikörper (ABIN2961828)

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Abeta 1-42 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Klon: Ab42-2

Produktdetails anti-Abeta 1-42 Antikörper

Spezifität: Reacts with human and mouse Aβx-42

Aufreinigung: Purified

Immunogen: Synthetic peptide corresponding to Abeta35-42.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
1 - 10 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS pH 7.4

Handhabung: Dilute in PBS or medium which is identical to that used in the assay system.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for at least one year at -20°C

Haltbarkeit: 12 months

Details zu Abeta 1-42

Target: Abeta 1-42 (Amyloid beta 1-42 (Abeta 1-42))

Andere Bezeichnung: Amyloid beta 1-42

Hintergrund: Accumulation and aggregation of amyloid β (Aβ) in the brain is indicated as the trigger of a pathological cascade that causes Alzheimer disease (AD). The highly amyloidogenic 42-amino acid form of Aβ (Aβ42) and amino-terminally truncated forms of Aβ (Aβx-42) are the predominant species of Aβ typically found in diffuse and senile plaques within the AD brain. The relative levels of Aβ42 appear to be the key regulators of Aβ aggregation into amyloid, thus Aβ42 has been implicated as the initiating molecule in the pathogenesis of AD.

Amyloid beta A4 protein ABPP APPI, APP Alzheimer disease amyloid protein Cerebral vascular amyloid peptide, CVAP PreA4 Protease nexin-II, PN-II Beta-amyloid protein 42 Beta-APP42 Gene name: APP, A4, AD1

Gen-ID: 351

UniProt: P05067