IL-13 Antikörper

Produktnummer ABIN289477

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch IL-13 in WB, ELISA und Inhibition. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für IL-13 Antikörper (ABIN289477)

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Produktdetails anti-IL-13 Antikörper

Aufreinigung: Affinity chromatography purified

Immunogen: IL13 antibody was raised in rabbit using highly pure recombinant human IL-13 as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-2 µg/mL, Inhibition: 0.12-0.15 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized from 0.5 x PBS, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu IL-13

Target: IL-13 (IL13) (Interleukin 13 (IL13))

Andere Bezeichnung: IL13

Hintergrund: IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL13 in mice resulted in impaired Th2 cell development and indicated an important role for IL13 in the expulsion of gastrointestinal parasites. IL13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL1beta, TNF-alpha, IL6 and IL8. IL13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL13 activity inhibits the pathophysiology of asthma. Human and Mouse IL13 is cross-species reactive.

Molekulargewicht: 12.3 kDa (predicted detection band MW)

Pathways: JAK-STAT Signalweg, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport