IL-11 Antikörper

Produktnummer ABIN289358

Der Kaninchen Polyklonal Anti-IL-11-Antikörper wurde für WB, ELISA und Inhibition validiert. Er ist geeignet, IL-11 in Proben von Human zu detektieren.

Kurzübersicht für IL-11 Antikörper (ABIN289358)

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL-11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Blocking Antibody (Inhibition)

Produktdetails anti-IL-11 Antikörper

Aufreinigung: Purified

Immunogen: IL11 antibody was raised in rabbit using highly pure recombinant hIL-11 as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.5-2 µg/mL, Inhibition: 0.02-0.05 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile water at a concentration of >0.2 mg/mL.

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.4.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu IL-11

Target: IL-11 (IL11) (Interleukin 11 (IL11))

Andere Bezeichnung: IL11

Hintergrund: IL11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.

Molekulargewicht: 19.1 kDa (predicted detection band MW)

Pathways: JAK-STAT Signalweg, Negative Regulation of Hormone Secretion