Resistin Antikörper (Biotin)

Produktnummer ABIN288464

Der Ziege Polyklonal anti-Resistin Antikörper wird verwendet zum Nachweis von Resistin in Proben von Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für Resistin Antikörper (Biotin) (ABIN288464)

Target: Resistin (RETN)

Reaktivität: Maus

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Resistin Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Resistin Antikörper (Biotin)

Immunogen: Resistin antibody (biotin) was raised in goat using highly pure recombinant murine resistin as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 0.25-1 µg/mL, WB: 0.1-0.2 µg/mL
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in sterile PBS with 0.1 % BSA to a concentration of at least 50 µg/mL

Konzentration: Lot specific

Buffer: Lyophilized from PBS, pH 7.2.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.

Details zu Resistin

Target: Resistin (RETN)

Andere Bezeichnung: Resistin

Hintergrund: Resistin belongs to a family of tissue-specific cytokines termed FIZZ (found in inflammatory zones) and RELM. The three known members of this family, Resistin, RELM-alpha and RELM-beta share a highly conserved C-terminal domain, characterized by 10 cysteine residues with a unique spacing motif of C-X11-C-X8-C-X-C-X3-C-X10-C-X-C-X-C-X9-C-C. Resistin is an adipose-derived cytokine (adipokine) whose physiological function and molecular targets are largely unknown. Studies have shown that Resistin suppresses insulin's ability to stimulate glucose uptake, and postulated that Resistin might be an important link between obesity and Type 2 diabetes. Other studies have indicated that Resistin expression is severely suppressed in obesity and that it may act as a feedback regulator of Adipogenesis.

Molekulargewicht: 20.2 kDa (predicted detection band MW)

Pathways: Feeding Behaviour, Smooth Muscle Cell Migration