Beclin 1 Antikörper (C-Term) (HRP)
Kurzübersicht für Beclin 1 Antikörper (C-Term) (HRP) (ABIN2868770)
Target
Alle Beclin 1 (BECN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Spezifität
- Predicted molecular weight at ~51 kDa.
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Peptide Affinity Purified
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Immunogen
- Synthetic peptide from the C-terminus of human Beclin 1
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Applikationshinweise
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- WB (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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Kommentare
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A 1:1000 dilution of ABIN2868770 was sufficient for detection of Beclin1 on 293T lysates using Goat anti-rabbit IgG:HRP as the secondary antibody.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Conjugated antibodies should be stored at 4°C
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- Beclin 1 (BECN1) (Beclin 1, Autophagy Related (BECN1))
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Andere Bezeichnung
- Beclin 1
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Hintergrund
- Beclin 1 is the mammalian ortholog of the yeast autophagy -related gene Atg6. It regulates autophagy and has an inportant role in development, tumorigenesis and neurodegeneration (1). Beclin 1 is localized within cytoplasmic structures including the mitochondria, yet overexpression reveals some nuclear staining (2). Researchers have found that schizonphrenia is associated with low levels of Beclin-1 in the hippocampus (3). It may also protect against infection by a neuorvirulent train of Sindbis virus (4).
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Gen-ID
- 8678
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NCBI Accession
- NP_001300927
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UniProt
- Q14457
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Pathways
- Autophagie
Target
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