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HYOU1 Antikörper (Atto 488)

This anti-HYOU1 antibody (ABIN2868630) is a Mouse Monoclonal antibody detecting HYOU1 in WB, IF, ICC. Suitable for Human.
Produktnummer ABIN2868630

Kurzübersicht für HYOU1 Antikörper (Atto 488) (ABIN2868630)

Target

Alle HYOU1 Antikörper anzeigen
HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

Reaktivität

  • 67
  • 29
  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 49
  • 18
Maus

Klonalität

  • 42
  • 26
Monoklonal

Konjugat

  • 29
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser HYOU1 Antikörper ist konjugiert mit Atto 488

Applikation

  • 53
  • 15
  • 15
  • 13
  • 13
  • 13
  • 12
  • 10
  • 8
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon

6E3-2C3
  • Spezifität

    Detects ~170 kDa.

    Kreuzreaktivität

    Human, Maus, Ratte

    Aufreinigung

    Protein G Purified

    Immunogen

    Recombinant Full length GRP170 Protein

    Isotyp

    IgG2b
  • Applikationshinweise

    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    Kommentare

    1 μg/ml of ABIN2868630 was sufficient for detection of GRP170 in 20 μg of HEK293 lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    Conjugated antibodies should be stored at 4°C
  • Target

    HYOU1 (Hypoxia Up Regulated 1 (HYOU1))

    Andere Bezeichnung

    GRP170

    Hintergrund

    GRP170, also known as ORP150, is the largest member of glucose-regulated Antibodys, and acts as a human chaperone Antibody. It is thought to play an important role in Antibody folding and secretion in the ER. Suppression of the Antibody is associated with accelerated apoptosis, therefore having an important cryoprotective role in hypoxia-induced cellular pertubation. This cryopotective role has led to an anti-tumor immune response, which will hopefully lead to therapeutic immunizations against cancers (1). GRP170 has also been shown to bind with dendritic cells and provide the danger signals to induce anti-tumor immune responses (2).

    Gen-ID

    10525

    NCBI Accession

    NP_006389

    UniProt

    Q9Y4L1

    Pathways

    ER-Nucleus Signaling, SARS-CoV-2 Protein Interaktom
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