SNCAIP Antikörper

Produktnummer ABIN285957

Produktdetails anti-SNCAIP Antikörper

Target: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser SNCAIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Immunogen: Synphilin 1 antibody was raised in goat using a peptide, SLELNGEKDKDKGRTLQRT, as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:10,655, IHC-P: >1:400, WB: >1:2,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu SNCAIP

Target: SNCAIP (Synuclein, alpha Interacting Protein (SNCAIP))

Andere Bezeichnung: Synphilin 1 (SNCAIP Produkte)

Hintergrund: Synphilin-1 is a cytoplasmic protein that is enriched in the neurophil of normal human brain. Although the exact function of synphilin-1 is unknown, it may possibly have a role as a cytoskeletal protein based on the presence of ankyrin-like repeats and an ATP, GTP-binding domain. It has been shown to be novel is its ability to associate in vivo with a-synuclein to form cytoplasmic eosinophilic inclusions. Additionally, it has been observed to be present in Lewy bodies of Parkinson disease, which are composed of a-synuclein. Because synphilin-1 is not found in protein aggregates of Alzheimer’s disease, it appears to be specific for a-synuclein-containing lesions. Synphilin-1 may facilitate the aggregation of a-synuclein into Lewy bodies.