8-OHDG Antikörper

Produktnummer ABIN285804

Dieses Anti-8-OHDG-Antikörper ist ein Ziege Polyklonal-Antikörper zur Detektion von 8-OHDG in ELISA und IHC. Geeignet für . Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für 8-OHDG Antikörper (ABIN285804)

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser 8-OHDG Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-8-OHDG Antikörper

Immunogen: 8-Hydroxyguanosine antibody was raised in goat using 8-Hydroxyguansoine as the immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: >1:250,000, IHC-P: >1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Supplied as liquid whole serum without preservative

Konservierungsmittel: Without preservative

Handhabung: Avoid repeated freeze/thaw cycles

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Referenzen für anti-8-OHDG Antikörper (ABIN285804)

Tuerdi, Kikuta, Kinoshita, Kamogashira, Kondo, Yamasoba: "Zone-specific damage of the olfactory epithelium under protein restriction." in: Scientific reports, Vol. 10, Issue 1, pp. 22175, (2021) (PubMed).

Jeannot, Pogribny, Beland, Rusyn: "Chronic administration of ethanol leads to an increased incidence of hepatocellular adenoma by promoting H-ras-mutated cells." in: Cancer letters, Vol. 301, Issue 2, pp. 161-7, (2011) (PubMed).

Details zu 8-OHDG

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Substanzklasse: Chemical

Hintergrund: 8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecules that eventually leads to several diseases in humans, such as arteriosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer?s disease.