8-OHDG Antikörper

Produktnummer ABIN111330

Der Maus Monoklonal anti-8-OHDG Antikörper (Klon 15A3) (ABIN111330) detektiert spezifisch 8-OHDG in EIA, IHC (fro) und IF.

Kurzübersicht für 8-OHDG Antikörper (ABIN111330)

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser 8-OHDG Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Klon: 15A3

Produktdetails anti-8-OHDG Antikörper

Aufreinigung: Protein G Chromatography.

Immunogen: 8-Hydroxyguanosine (OH8G)-BSA and -casein conjugates.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Suitable for use in ELISA and Immunohistochemistry (PLP-fixed sections) to detect themarkers of oxidative damage to DNA and RNA. May also be used on Immunoaffinity columns to isolate oxidative DNA damage adductsfrom biological fluids.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL (OD 280 nm)

Buffer: TBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Details zu 8-OHDG

Target: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Andere Bezeichnung: 8-Hydroxy-Guanosine / 8-OHG

Substanzklasse: Chemical

Hintergrund: 8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2'deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke.Synonyms: 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG