GRP78 Antikörper (C-Term)

Produktnummer ABIN285796

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GRP78 in WB. Er zeigt eine Reaktivität gegenüber Ratte.

Kurzübersicht für GRP78 Antikörper (C-Term) (ABIN285796)

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRP78 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GRP78 Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Maus, Ratte (Rattus), Rind (Kuh), Eumycota, Hamster, Primate, Kaninchen, Xenopus laevis

Aufreinigung: Affinity purified

Immunogen: Grp78 antibody was raised in rabbit using a synthetic peptide corresponding to the sequence near the C-terminus of rat Grp78 (BiP) as the immunogen.

Anwendungsinformationen

Applikationshinweise: 1:1,000
Optimal conditions should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Neat Serum with no preservatives.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Handhabung: Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C for short term storage. Aliquot and store at -20 °C for long term storage.

Details zu GRP78

Target: GRP78 (HSPA5) (Heat Shock 70kDa Protein 5 (Glucose-Regulated Protein, 78kDa) (HSPA5))

Andere Bezeichnung: Grp78

Hintergrund: Binding immunoglobulin protein (BiP) also known as 78 kDa glucose-regulated protein (GRP-78) or heat shock 70 kDa protein 5 (HSPA5) is a HSP70 molecular chaperone located in the lumen of the endoplasmic reticulum (ER), that binds newly-synthesized proteins as they are translocated into the ER and maintains them in a state competent for subsequent folding and oligomerization.

Pathways: Thyroid Hormone Synthesis, ER-Nucleus Signaling