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DDB1 Antikörper (C-Term)

KO Validated DDB1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2857079
  • Target Alle DDB1 Antikörper anzeigen
    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
    Bindungsspezifität
    • 8
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 45
    • 22
    • 19
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 36
    • 8
    • 1
    Kaninchen
    Klonalität
    • 35
    • 10
    Polyklonal
    Konjugat
    • 34
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DDB1 Antikörper ist unkonjugiert
    Applikation
    • 30
    • 15
    • 13
    • 12
    • 10
    • 10
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Kreuzreaktivität
    Human, Maus, Ratte
    Produktmerkmale
    Rabbit Polyclonal antibody to DDB1 (damage-specific DNA binding protein 1, 127 kDa)
    DDB1 antibody
    Aufreinigung
    Purified by antigen-affinity chromatography.
    Güteklasse
    KO Validated
    Immunogen
    Recombinant protein encompassing a sequence within the C-terminus region of human DDB1. The exact sequence is proprietary.
    Isotyp
    IgG
    Top Product
    Discover our top product DDB1 Primärantikörper
  • Applikationshinweise
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    Kommentare

    Positive Control: NIH-3T3 , Mouse brain , PC-12 , Rat2 , rat brain , 293T

    Validation: KO/KD

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.34 mg/mL
    Buffer
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target
    DDB1 (Damage Specific DNA Binding Protein 1 (DDB1))
    Andere Bezeichnung
    damage specific DNA binding protein 1 (DDB1 Produkte)
    Synonyme
    DDBA antikoerper, UV-DDB1 antikoerper, XAP1 antikoerper, XPCE antikoerper, XPE antikoerper, XPE-BF antikoerper, DDB1 antikoerper, xpe antikoerper, ddba antikoerper, xap1 antikoerper, xpce antikoerper, xpe-bf antikoerper, uv-ddb1 antikoerper, ddb1 antikoerper, 127kDa antikoerper, AA408517 antikoerper, p127-Ddb1 antikoerper, damage specific DNA binding protein 1 antikoerper, damage-specific DNA binding protein 1, 127kDa antikoerper, DNA damage-binding protein 1 antikoerper, damage-specific DNA binding protein 1 antikoerper, DDB1 antikoerper, ddb1 antikoerper, LOC100187356 antikoerper, Ddb1 antikoerper, ddb-1 antikoerper
    Hintergrund
    This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However, it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition, Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q, but no sequence alternations of this gene are demonstrated in Best disease patients.

    Cellular Localization: Cytoplasm , Nucleus
    Molekulargewicht
    127 kDa
    Gen-ID
    1642
    UniProt
    Q16531
    Pathways
    DNA Reparatur
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