LHCGR Antikörper (C-Term)

Produktnummer ABIN2857013

Der Kaninchen Polyklonal Anti-LHCGR-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, LHCGR in Proben von Human zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für LHCGR Antikörper (C-Term) (ABIN2857013)

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LHCGR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-LHCGR Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit Polyclonal antibody to LHR (luteinizing hormone/choriogonadotropin receptor)
LHR antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human LHR. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: H1299

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-LHCGR Antikörper (ABIN2857013)

Liu, Hsu, Chen, Chiu, Lin: "A Tri-fusion Reporter Mouse Reveals Tissue-Specific FGF1B Promoter Activity in vivo." in: Scientific reports, Vol. 9, Issue 1, pp. 11143, (2019) (PubMed).

Wu, Wang, Chueh, Yang, Huang, Lin, Wang, Connolly, Hu, Gomez-Sanchez, Peng, Wu: "The prevalence of CTNNB1 mutations in primary aldosteronism and consequences for clinical outcomes." in: Scientific reports, Vol. 7, pp. 39121, (2018) (PubMed).

Details zu LHCGR

Target: LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

Andere Bezeichnung: luteinizing hormone/choriogonadotropin receptor

Hintergrund: This gene encodes the receptor for both luteinizing hormone and choriogonadotropin. This receptor belongs to the G-protein coupled receptor 1 family, and its activity is mediated by G proteins which activate adenylate cyclase. Mutations in this gene result in disorders of male secondary sexual character development, including familial male precocious puberty, also known as testotoxicosis, hypogonadotropic hypogonadism, Leydig cell adenoma with precocious puberty, and male pseudohermaphtoditism with Leydig cell hypoplasia.

Cellular Localization: Cell membrane, Multi-pass membrane protein

Molekulargewicht: 79 kDa

Gen-ID: 3973

UniProt: P22888

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagie, Negative Regulation of intrinsic apoptotic Signaling