BCL2L10 Antikörper

Produktnummer ABIN2856828

Dieses Anti-BCL2L10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BCL2L10 in WB, IF, ICC und IHC (p). Geeignet für Human.

Kurzübersicht für BCL2L10 Antikörper (ABIN2856828)

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BCL2L10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-BCL2L10 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit polyclonal antibody to BCL2L10 (BCL2-like 10 (apoptosis facilitator))
BCL2L10 antibody [N2C2], Internal

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.32 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu BCL2L10

Target: BCL2L10 (BCL2-Like 10 (Apoptosis Facilitator) (BCL2L10))

Andere Bezeichnung: BCL2 like 10

Hintergrund: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Cellular Localization: Mitochondrion , Nucleus membrane

Molekulargewicht: 22 kDa

Gen-ID: 10017

UniProt: Q9HD36

Pathways: Positive Regulation of Endopeptidase Activity