SENP2 Antikörper (N-Term)

Produktnummer ABIN2856760

Produktdetails anti-SENP2 Antikörper

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SENP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)

Kreuzreaktivität: Rind (Kuh)

Kreuzreaktivität (Details): Bovine (88 %)

Produktmerkmale: Rabbit Polyclonal antibody to SENP2 (sentrin-specific protease 2)
SENP2 antibody [N1], N-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SENP2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , Molt-4

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-SENP2 Antikörper (ABIN2856760)

Zhou, Zheng, Hu, Wang, Zhang, Zou, Zhong, Wang, Wu, Kang: "SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).

Details zu SENP2

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Andere Bezeichnung: SENP2 (SENP2 Produkte)

Synonyme: 2310007L05Rik antikoerper, 4930538C18Rik antikoerper, AI646780 antikoerper, AW554757 antikoerper, Smt3ip2 antikoerper, SuPr-1 antikoerper, mKIAA1331 antikoerper, AXAM2 antikoerper, SMT3IP2 antikoerper, Axam antikoerper, SUMO/sentrin specific peptidase 2 antikoerper, SUMO1/sentrin/SMT3 specific peptidase 2 antikoerper, Sumo1/sentrin/SMT3 specific peptidase 2 antikoerper, Senp2 antikoerper, SENP2 antikoerper

Hintergrund: SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM]

Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side , Cytoplasm

Molekulargewicht: 68 kDa

Gen-ID: 59343

Pathways: Chromatin Binding