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SENP2 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SENP2 in WB, IHC (p), IF und ICC. Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2856760

Kurzübersicht für SENP2 Antikörper (N-Term) (ABIN2856760)

Target

Alle SENP2 Antikörper anzeigen
SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Reaktivität

  • 39
  • 32
  • 7
  • 5
  • 5
  • 2
  • 2
  • 2
  • 2
  • 1
Human

Wirt

  • 48
  • 7
Kaninchen

Klonalität

  • 48
  • 7
Polyklonal

Konjugat

  • 26
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SENP2 Antikörper ist unkonjugiert

Applikation

  • 45
  • 20
  • 19
  • 13
  • 13
  • 11
  • 9
  • 4
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Kreuzreaktivität

    Rind (Kuh)

    Kreuzreaktivität (Details)

    Bovine (88 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to SENP2 (sentrin-specific protease 2)
    SENP2 antibody [N1], N-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SENP2. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

    Kommentare

    Positive Control: 293T , Molt-4

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Zhou, Zheng, Hu, Wang, Zhang, Zou, Zhong, Wang, Wu, Kang: "SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).

  • Target

    SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

    Andere Bezeichnung

    SENP2

    Hintergrund

    SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM]

    Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side , Cytoplasm

    Molekulargewicht

    68 kDa

    Gen-ID

    59343

    Pathways

    Chromatin Binding
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