SENP2 Antikörper (N-Term)
Kurzübersicht für SENP2 Antikörper (N-Term) (ABIN2856760)
Target
Alle SENP2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Rind (Kuh)
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Kreuzreaktivität (Details)
- Bovine (88 %)
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Produktmerkmale
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Rabbit Polyclonal antibody to SENP2 (sentrin-specific protease 2)
SENP2 antibody [N1], N-term -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SENP2. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
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Kommentare
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Positive Control: 293T , Molt-4
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).
: "
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SUMOylation stabilizes hSSB1 and enhances the recruitment of NBS1 to DNA damage sites." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 80, (2020) (PubMed).
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- SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))
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Andere Bezeichnung
- SENP2
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Hintergrund
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SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM]
Cellular Localization: Nucleus , nuclear pore complex , Nucleus membrane, Peripheral membrane protein, Nucleoplasmic side , Cytoplasm -
Molekulargewicht
- 68 kDa
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Gen-ID
- 59343
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Pathways
- Chromatin Binding
Target
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