TEAD4 Antikörper (Center)

Produktnummer ABIN2856634

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TEAD4 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für TEAD4 Antikörper (Center) (ABIN2856634)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TEAD4 Antikörper

Bindungsspezifität: Center

Kreuzreaktivität: Maus, Schwein

Kreuzreaktivität (Details): Mouse (91 %), Pig (94 %)

Produktmerkmale: Rabbit Polyclonal antibody to TEAD4 (TEA domain family member 4)
TEAD4 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human TEAD4. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: HepG2 necleus

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-TEAD4 Antikörper (ABIN2856634)

Zhang, Li, Wu, Ge, Song, Wang, Yuan, Jiang, Wang, Cheng: "TEAD4 overexpression promotes epithelial-mesenchymal transition and associates with aggressiveness and adverse prognosis in head neck squamous cell carcinoma." in: Cancer cell international, Vol. 18, pp. 178, (2018) (PubMed).

Details zu TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Andere Bezeichnung: TEAD4

Hintergrund: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. Alternatively spliced transcripts encoding distinct isoforms, some of which are translated through the use of a non-AUG (UUG) initiation codon, have been described for this gene.

Cellular Localization: Nucleus

Molekulargewicht: 48 kDa

Gen-ID: 7004

Pathways: Regulation of Lipid Metabolism by PPARalpha