TEAD4 Antikörper (C-Term)

Produktnummer ABIN2780491

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TEAD4 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund und Zebrafisch (Danio rerio).Es wurde in 1 Publikation zitiert.

Kurzübersicht für TEAD4 Antikörper (C-Term) (ABIN2780491)

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TEAD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TEAD4 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: TEAD4 Antibody - C-terminal region

Sequenz: MMNSVLENFT ILQVVTNRDT QETLLCIAYV FEVSASEHGA QHHIYRLVKE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TEAD4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TEAD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8113597

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TEAD4 Antikörper (ABIN2780491)

Ribas, Moncaut, Siligan, Taylor, Cross, Rigby, Carvajal: "Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments." in: Developmental biology, Vol. 355, Issue 2, pp. 372-80, (2011) (PubMed).

Details zu TEAD4

Target: TEAD4 (TEA Domain Family Member 4 (TEAD4))

Andere Bezeichnung: TEAD4

Hintergrund:

Background Information: TEAD4 is a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. TEAD4 is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. TEAD4 is encoded through the use of a non-AUG (TTG) translation initiation codon. This gene encodes a member of the transcriptional enhancer factor (TEF) family. The family members contain the TEA/ATTS DNA-binding domain. This member is preferentially expressed in skeletal muscle, and binds to the M-CAT regulatory element which directs muscle-specific gene expression. The protein is encoded through the use of a non-AUG (TTG) translation initiation codon. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene Name: TEA domain family member 4

Alternative Symbols: TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B

Protein Name: Transcriptional enhancer factor TEF-3

Molekulargewicht: 48kDa

Gen-ID: 7004

NCBI Accession: NP_003204

UniProt: Q96BK2

Pathways: Regulation of Lipid Metabolism by PPARalpha