TJP1 Antikörper (N-Term)
Kurzübersicht für TJP1 Antikörper (N-Term) (ABIN2856624)
Target
Alle TJP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- N-Term
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
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Rabbit Polyclonal antibody to ZO-1 (tight junction protein 1 (zona occludens 1))
ZO-1 antibody [N1N2], N-term -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the N-terminus region of human ZO-1. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: HeLa
Validation: KO/KD
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.22 mg/mL
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Buffer
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models." in: Cell & bioscience, Vol. 9, pp. 40, (2019) (PubMed).
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Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models." in: Cell & bioscience, Vol. 9, pp. 40, (2019) (PubMed).
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- TJP1 (Tight Junction Protein 1 (TJP1))
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Andere Bezeichnung
- tight junction protein 1
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Hintergrund
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This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. The encoded protein may be involved in signal transduction at cell-cell junctions. Two transcript variants encoding distinct isoforms have been identified for this gene.
Cellular Localization: Cell membrane, Peripheral membrane protein, Cytoplasmic side , Cell junction , tight junction -
Molekulargewicht
- 195 kDa
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Gen-ID
- 7082
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UniProt
- Q07157
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Pathways
- Carbohydrate Homeostasis, Cell-Cell Junction Organization
Target
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