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RGS14 Antikörper (C-Term)

Der Kaninchen Polyklonal Anti-RGS14-Antikörper wurde für WB und IHC (p) validiert. Er ist geeignet, RGS14 in Proben von Human zu detektieren.
Produktnummer ABIN2856368

Kurzübersicht für RGS14 Antikörper (C-Term) (ABIN2856368)

Target

Alle RGS14 Antikörper anzeigen
RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

Reaktivität

  • 42
  • 33
  • 27
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 54
  • 8
  • 1
  • 1
Kaninchen

Klonalität

  • 57
  • 5
  • 1
Polyklonal

Konjugat

  • 36
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RGS14 Antikörper ist unkonjugiert

Applikation

  • 52
  • 22
  • 13
  • 13
  • 9
  • 7
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 15
    • 7
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    Kreuzreaktivität

    Human

    Produktmerkmale

    Rabbit Polyclonal antibody to RGS14 (regulator of G-protein signaling 14)
    RGS14 antibody [C3], C-term

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS14. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Jurkat

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.93 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

    Andere Bezeichnung

    regulator of G protein signaling 14

    Hintergrund

    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

    Cellular Localization: Membrane

    Molekulargewicht

    61 kDa

    Gen-ID

    10636

    UniProt

    O43566

    Pathways

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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