CTNNA1 Antikörper
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- Target Alle CTNNA1 Antikörper anzeigen
- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CTNNA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Cat, Hund, Human, Maus, Ratte
- Produktmerkmale
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Rabbit Polyclonal antibody to alpha 1 Catenin (catenin (cadherin-associated protein), alpha 1, 102 kDa)
alpha 1 Catenin antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human alpha 1 Catenin. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product CTNNA1 Primärantikörper
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- Applikationshinweise
- WB: 1:500-1:10000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- Kommentare
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Positive Control: Mouse brain , rat brain
Validation: Orthogonal
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1.11 mg/mL
- Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CTNNA1 (Catenin (Cadherin-Associated Protein), alpha 1, 102kDa (CTNNA1))
- Andere Bezeichnung
- catenin alpha 1 (CTNNA1 Produkte)
- Synonyme
- CAP102 antikoerper, 2010010M04Rik antikoerper, AA517462 antikoerper, AI988031 antikoerper, Catna1 antikoerper, CG17947 antikoerper, CT39986 antikoerper, Dalpha-Cat antikoerper, Dalpha-cat antikoerper, DalphaC antikoerper, Dalphacat antikoerper, Dmcatp antikoerper, Dmel\\CG17947 antikoerper, a-Cat antikoerper, a-cat antikoerper, alpha-CAT antikoerper, alpha-cat antikoerper, alpha-catenin antikoerper, alpha-ctn antikoerper, alphaCAT antikoerper, alphaCat antikoerper, alphacat antikoerper, Alpha-Cat antikoerper, dgri_GLEANR_3829 antikoerper, DgriGH19548 antikoerper, GH19548 antikoerper, ctnna antikoerper, cap102 antikoerper, catna1 antikoerper, ctnna1 antikoerper, catenin alpha 1 antikoerper, catenin (cadherin associated protein), alpha 1 antikoerper, alpha Catenin antikoerper, catenin alpha-1 antikoerper, catenin (cadherin-associated protein), alpha 1 antikoerper, catenin alpha 1 S homeolog antikoerper, CTNNA1 antikoerper, Ctnna1 antikoerper, alpha-Cat antikoerper, Dgri\alpha-Cat antikoerper, Tsp_10127 antikoerper, ctnna1 antikoerper, ctnna1.S antikoerper
- Hintergrund
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Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
Cellular Localization: Cytoplasm , cytoskeleton , Cell junction , adherens junction , Cell membrane - Molekulargewicht
- 100 kDa
- Gen-ID
- 1495
- UniProt
- P35221
- Pathways
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Maintenance of Protein Location
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