HSPB8 Antikörper (C-Term)

Produktnummer ABIN2855960

Produktdetails anti-HSPB8 Antikörper

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Kreuzreaktivität: Maus, Ratte (Rattus), Hund, Rhesusaffen, Rind (Kuh)

Kreuzreaktivität (Details): Mouse (85 %), Rat (85 %), Dog (100 %), Rhesus Monkey (100 %), Bovine (92 %)

Produktmerkmale: Rabbit Polyclonal antibody to HSP22 (heat shock 22 kDa protein 8)
HSP22 antibody [C2C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HSP22. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

Kommentare:

Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: HSP22 (HSPB8 Produkte)

Synonyme: CMT2L antikoerper, DHMN2 antikoerper, E2IG1 antikoerper, H11 antikoerper, HMN2 antikoerper, HMN2A antikoerper, HSP22 antikoerper, MGC64408 antikoerper, hsc70 antikoerper, wu:fb01g06 antikoerper, wu:fi48b06 antikoerper, fc09c11 antikoerper, wu:fc04b04 antikoerper, wu:fc09c11 antikoerper, zgc:64202 antikoerper, AU018630 antikoerper, AW413033 antikoerper, Cryac antikoerper, D5Ucla4 antikoerper, H11K antikoerper, HSP20-like antikoerper, Hsp22 antikoerper, heat shock protein family B (small) member 8 antikoerper, heat shock protein family B (small) member 8 L homeolog antikoerper, heat shock protein 8 antikoerper, heat shock protein b8 antikoerper, HSPB8 antikoerper, hspb8.L antikoerper, hspa8 antikoerper, hspb8 antikoerper, Hspb8 antikoerper

Hintergrund: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Molekulargewicht: 22 kDa

Gen-ID: 26353