PDE4D Antikörper (C-Term)

Produktnummer ABIN2855885

Der Kaninchen Polyklonal Anti-PDE4D-Antikörper wurde für WB, ICC, IF und IHC (p) validiert. Er ist geeignet, PDE4D in Proben von Human zu detektieren.

Kurzübersicht für PDE4D Antikörper (C-Term) (ABIN2855885)

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDE4D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDE4D Antikörper

Bindungsspezifität: C-Term

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to PDE4D (phosphodiesterase 4D, cAMP-specific)
PDE4D antibody [C3], C-term

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PDE4D. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: A431 , HeLa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.3 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Konservierungsmittel: Thimerosal (Merthiolate)

Vorsichtsmaßnahmen: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Details zu PDE4D

Target: PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

Andere Bezeichnung: phosphodiesterase 4D

Hintergrund: The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells (Dominiczak and McBride, 2003 [PubMed 14517535]).[supplied by OMIM]

Cellular Localization: Cytoplasm (By similarity) , Membrane (By similarity) , Cytoplasm , cytoskeleton (By similarity) , Centrosome (By similarity)

Molekulargewicht: 91 kDa

Gen-ID: 5144

UniProt: Q08499

Pathways: Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling