IDH3A Antikörper
Kurzübersicht für IDH3A Antikörper (ABIN2855763)
Target
Alle IDH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio)
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Produktmerkmale
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Rabbit Polyclonal antibody to IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha)
IDH3A antibody -
Aufreinigung
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.
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Isotyp
- IgG
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Applikationshinweise
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Kommentare
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Positive Control: Mouse brain , rat brain
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.84 mg/mL
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Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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Konservierungsmittel
- Thimerosal (Merthiolate)
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Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))
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Andere Bezeichnung
- isocitrate dehydrogenase 3 (NAD(+)) alpha
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Hintergrund
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.
Cellular Localization: Mitochondrion -
Molekulargewicht
- 40 kDa
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Gen-ID
- 3419
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UniProt
- P50213
Target
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