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IDH3A Antikörper

Dieses Anti-IDH3A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von IDH3A in WB, IF, IHC (p) und ICC. Geeignet für Human.
Produktnummer ABIN2855763

Kurzübersicht für IDH3A Antikörper (ABIN2855763)

Target

Alle IDH3A Antikörper anzeigen
IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

Reaktivität

  • 46
  • 33
  • 19
  • 7
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 41
  • 4
  • 1
Kaninchen

Klonalität

  • 43
  • 3
Polyklonal

Konjugat

  • 21
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IDH3A Antikörper ist unkonjugiert

Applikation

  • 34
  • 13
  • 13
  • 13
  • 13
  • 9
  • 5
  • 3
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Kreuzreaktivität

    Human, Maus, Ratte, Zebrafisch (Danio rerio)

    Produktmerkmale

    Rabbit Polyclonal antibody to IDH3A (isocitrate dehydrogenase 3 (NAD+) alpha)
    IDH3A antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human IDH3A. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Kommentare

    Positive Control: Mouse brain , rat brain

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.84 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    IDH3A (Isocitrate Dehydrogenase 3 (NAD+) alpha (IDH3A))

    Andere Bezeichnung

    isocitrate dehydrogenase 3 (NAD(+)) alpha

    Hintergrund

    Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase.

    Cellular Localization: Mitochondrion

    Molekulargewicht

    40 kDa

    Gen-ID

    3419

    UniProt

    P50213
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