RFC4 Antikörper
Kurzübersicht für RFC4 Antikörper (ABIN2855757)
Target
Alle RFC4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
- 
    - 
                                            Kreuzreaktivität
- Human, Maus
- 
                                            Produktmerkmale
- 
                        Rabbit Polyclonal antibody to RFC4 (replication factor C (activator 1) 4, 37 kDa)
 RFC4 antibody [N1C3]
- 
                                            Aufreinigung
- Purified by antigen-affinity chromatography.
- 
                                            Immunogen
- Recombinant protein encompassing a sequence within the center region of human RFC4. The exact sequence is proprietary.
- 
                                            Isotyp
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            Applikationshinweise
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 
                                            Kommentare
- 
                        Positive Control: Mouse liver , 293T , A431 , HeLa , HepG2 
- 
                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
- 
                                            
- 
    - 
                                            Format
- Liquid
- 
                                            Konzentration
- 0.62 mg/mL
- 
                                            Buffer
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 
                                            Konservierungsmittel
- Thimerosal (Merthiolate)
- 
                                            Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            Lagerung
- 4 °C,-20 °C
- 
                                            Informationen zur Lagerung
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
 
- 
                                            
- 
    - RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
- 
                                            Andere Bezeichnung
- replication factor C subunit 4
- 
                                            Hintergrund
- 
                        The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported. 
 Cellular Localization: Nucleus
- 
                                            Molekulargewicht
- 40 kDa
- 
                                            Gen-ID
- 5984
- 
                                            UniProt
- P35249
- 
                                            Pathways
- Telomere Maintenance, DNA Reparatur, DNA Replication, Synthesis of DNA
 Target
- 
                    
 
                                     
                                     
                                    