EIF4E2 Antikörper

Produktnummer ABIN2855740

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EIF4E2 in WB und IP. Er zeigt eine Reaktivität gegenüber Human und wurde in 2+ Publikationen erwähnt.

Kurzübersicht für EIF4E2 Antikörper (ABIN2855740)

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF4E2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Güteklasse: KO Validated

Produktdetails anti-EIF4E2 Antikörper

Kreuzreaktivität: Human, Maus

Produktmerkmale: Rabbit polyclonal antibody to EIF4EL3 (eukaryotic translation initiation factor 4E family member 2)
EIF4E2 antibody [N1C3]

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human EIF4E2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Validation: KO/KD

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.27 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-EIF4E2 Antikörper (ABIN2855740)

Juszkiewicz, Slodkowicz, Lin, Freire-Pritchett, Peak-Chew, Hegde: "Ribosome collisions trigger cis-acting feedback inhibition of translation initiation." in: eLife, Vol. 9, (2020) (PubMed).

Garzia, Jafarnejad, Meyer, Chapat, Gogakos, Morozov, Amiri, Shapiro, Molina, Tuschl, Sonenberg: "The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs." in: Nature communications, Vol. 8, pp. 16056, (2018) (PubMed).

Details zu EIF4E2

Target: EIF4E2 (Eukaryotic Translation Initiation Factor 4E Family Member 2 (EIF4E2))

Andere Bezeichnung: eukaryotic translation initiation factor 4E family member 2

Hintergrund: Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures.

Molekulargewicht: 28 kDa

Gen-ID: 9470

UniProt: O60573

Pathways: SARS-CoV-2 Protein Interaktom