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RAD23B Antikörper (Center)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RAD23B in WB, IF, IHC (p) und ICC. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN2855629

Kurzübersicht für RAD23B Antikörper (Center) (ABIN2855629)

Target

Alle RAD23B Antikörper anzeigen
RAD23B (RAD23 Homolog B (RAD23B))

Reaktivität

  • 89
  • 38
  • 36
  • 6
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Wirt

  • 66
  • 22
  • 1
Kaninchen

Klonalität

  • 67
  • 22
Polyklonal

Konjugat

  • 54
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RAD23B Antikörper ist unkonjugiert

Applikation

  • 68
  • 30
  • 26
  • 16
  • 14
  • 14
  • 13
  • 12
  • 10
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
  • Bindungsspezifität

    • 15
    • 8
    • 7
    • 6
    • 6
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    Kreuzreaktivität

    Rind (Kuh)

    Kreuzreaktivität (Details)

    Bovine (91 %)

    Produktmerkmale

    Rabbit Polyclonal antibody to hHR23b (RAD23 homolog B (S. cerevisiae))
    hHR23b antibody

    Aufreinigung

    Purified by antigen-affinity chromatography.

    Immunogen

    Recombinant protein encompassing a sequence within the center region of human RAD23B. The exact sequence is proprietary.

    Isotyp

    IgG
  • Applikationshinweise

    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:5000-1:20000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:5000-1:20000*

    Kommentare

    Positive Control: 293T , A431

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.69 mg/mL

    Buffer

    0.1M Tris, 0.1M Glycine, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

    Konservierungsmittel

    Thimerosal (Merthiolate)

    Vorsichtsmaßnahmen

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Target

    RAD23B (RAD23 Homolog B (RAD23B))

    Andere Bezeichnung

    hHR23b

    Hintergrund

    The protein encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

    Cellular Localization: Nucleus , Cytoplasm

    Molekulargewicht

    43 kDa

    Gen-ID

    5887

    Pathways

    DNA Reparatur
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