LAMP2 Antikörper

Produktnummer ABIN2855580

Dieses Anti-LAMP2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LAMP2 in WB, ICC, IF und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für LAMP2 Antikörper (ABIN2855580)

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LAMP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: KO Validated

Produktdetails anti-LAMP2 Antikörper

Kreuzreaktivität: Human

Produktmerkmale: Rabbit Polyclonal antibody to LAMP2 (lysosomal-associated membrane protein 2)
LAMP2 antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human LAMP2. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Validatio: KO/KD, Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.63 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-LAMP2 Antikörper (ABIN2855580)

Kuo, Lin, Hsu, Chen, Yang, Wu: "Noninvasive assessment of characteristics of novel anti-HER2 antibodies by molecular imaging in a human gastric cancer xenograft-bearing mouse model." in: Scientific reports, Vol. 8, Issue 1, pp. 13735, (2019) (PubMed).

Izumi, Li, Shibaki, Mori, Yasunami, Sato, Matsunaga, Mae, Kodama, Kamijo, Kaneko, Nakagawara: "Recycling endosomal CD133 functions as an inhibitor of autophagy at the pericentrosomal region." in: Scientific reports, Vol. 9, Issue 1, pp. 2236, (2019) (PubMed).

Details zu LAMP2

Target: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Andere Bezeichnung: lysosomal associated membrane protein 2

Hintergrund: The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins.

Cellular Localization: Cell membrane, Single-pass type I membrane protein , Endosome membrane, Single-pass type I membrane protein , Lysosome membrane, Single-pass type I membrane protein

Molekulargewicht: 45 kDa

Gen-ID: 3920

UniProt: P13473

Pathways: Autophagie